Ethanol → Ethyl 7-methoxy-9-oxoxanthene-2-carboxylate

HRID 435999

반응식

HRID 435999 반응식
[CH3:1][O:2][C:3]1[CH:16]=[C:15]2[C:6]([O:7][C:8]3[CH:9]=[CH:10][C:11]([C:18]([OH:20])=[O:19])=[CH:12][C:13]=3[C:14]2=[O:17])=[CH:5][CH:4]=1.[CH2:21](O)[CH3:22]>S(=O)(=O)(O)O>[CH3:1][O:2][C:3]1[CH:16]=[C:15]2[C:6]([O:7][C:8]3[CH:9]=[CH:10][C:11]([C:18]([O:20][CH2:21][CH3:22])=[O:19])=[CH:12][C:13]=3[C:14]2=[O:17])=[CH:5][CH:4]=1

참가 물질

4

반응물 2

HCID 702EthanolHCID 1931602-Carboxy-7-methoxyxanthen-9-one

생성물 1

HCID 21455094Ethyl 7-methoxy-9-oxoxanthene-2-carboxylate수율 84%

시약·촉매·용매 1

HCID 1118Sulfuric Acid용매

실험 절차

A mixture of 7-methoxy-9-oxoxanthene-2-carboxylic acid in ethanol (100ml) and concentrated sulfuric acid (10 ml) was refluxed under nitrogen for 24 hours. The reaction mixture was concentrated and cooled. The product, which precipitated, was filtered off and recrystallized from ethanol to give white crystals (2.53g, 84%), mp. 170°-172° C.

후처리

  1. temperaturewas refluxed under nitrogen for 24 hours
  2. concentrationThe reaction mixture was concentrated
  3. temperaturecooled
  4. customThe product, which precipitated
  5. filtrationwas filtered off
  6. customrecrystallized from ethanol

출처 및 근거

ORD 기록
ord-675d50573a774e7fad237b71e5dc3df1
출처 데이터셋
uspto-grants-1977_02
특허 번호
US04007205

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