Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Phenyl Isothiocyanate → 1-[4-(2-Acetylhydrazino)phenyl]-3-phenylthiourea
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Phenyl Isothiocyanate | HCID 7673 | — |
| 반응물 | Acetic acid, 2-(4-aminophenyl)hydrazide | HCID 81068 | — |
| 용매 | Acetonitrile | HCID 6342 | — |
| 생성물 | 1-[4-(2-Acetylhydrazino)phenyl]-3-phenylthiourea | HCID 21427808 | — |
반응 단계
1-Acetyl-2-(4-aminophenyl)hydrazine (8.25 g, 0.05 mole) and phenyl isothiocyanate (6.8 g, 0.05 mole) were suspended in acetonitrile (100 ml). The resulting mixture was heated at reflux with stirring for 5 minutes. The product separated from solution as a white solid. After chilling, the product was removed from the reaction mixture by filtration and washed thoroughly with ether. Yield 14.5 g (96%), m.p. 205°-207° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04030925 |
| 출처 데이터셋 | uspto-grants-1977_06 |
| ORD ID | ord-a7b5c2b53aa04f22ac27f81cac58c183 |
| 출처 메모 | uspto-grants-1977_06 |