참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Acetic Anhydride | HCID 7918 | — |
| 반응물 | p-Nitrobenzyl 7-Phenoxyacetamido-3-methylenecepham-4-carboxylate-1-oxide | HCID 12780262 | — |
| 촉매 | Acetyl chloride | HCID 6367 | — |
| 용매 | Benzene | HCID 241 | — |
| 생성물 | p-Nitrobenzyl 7-phenoxyacetamido-3-acetoxymethyl-2-cephem-4-carboxylate | HCID 70634984 | — |
반응 단계
To 10 ml. of benzene were added 500 mg. (1 millimole) of p-nitrobenzyl 7-phenoxyacetamido-3-methylenecepham-4-carboxylate-1-oxide. To the resulting slurry were added 2 ml. of acetic anhydride and 2 drops of acetyl chloride. The resulting mixture was refluxed at 85° C. for about 15 hours. The resulting reaction mixture then was treated as in Example 1 to obtain p-nitrobenzyl 7-phenoxyacetamido-3-acetoxymethyl-2-cephem-4-carboxylate.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US04031082 |
|---|
| 출처 데이터셋 | uspto-grants-1977_06 |
|---|
| ORD ID | ord-22f5b702ee9a4d969ac79f9845416e94 |
|---|
| 출처 메모 | uspto-grants-1977_06 |
|---|
