Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Phenyl chloroformate → 1-Phenoxycarbonyl-3-(p-fluorophenoxy)azetidine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Phenyl chloroformate | HCID 15891 | — |
| 반응물 | 1-Benzhydryl-3-(4-fluorophenoxy)azetidine | HCID 15053369 | — |
| 용매 | Toluene | HCID 1140 | — |
| 생성물 | 1-Phenoxycarbonyl-3-(p-fluorophenoxy)azetidine | HCID 21428738 | — |
반응 단계
A solution of 20.0 g of 1-benzhydryl-3-(4-fluorophenoxy)azetidine and 10.3 g of phenylchloroformate in 200 ml. of toluene is refluxed for 16 hours. The reaction mixture is cooled, and the toluene is removed under reduced pressure to give a yellow oil. The oil is triturated with hexane to give a white solid of 1-phenoxycarbonyl-3-(p-fluorophenoxy)azetidine.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04031221 |
| 출처 데이터셋 | uspto-grants-1977_06 |
| ORD ID | ord-f1f12d4a48a34596b18ae613aeac5c68 |
| 출처 메모 | uspto-grants-1977_06 |