Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Phthalic Anhydride → 2-(4-(Diethylamino)-2-methylbenzoyl)benzoic acid
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Phthalic Anhydride | HCID 6811 | — |
| 반응물 | Chlorobenzene | HCID 7964 | — |
| 반응물 | N,N-diethyl-m-toluidine | HCID 66679 | — |
| 반응물 | Aluminum(III) Chloride | HCID 6451240 | — |
| 용매 | Water | HCID 962 | — |
| 생성물 | 2-(4-(Diethylamino)-2-methylbenzoyl)benzoic acid | HCID 104335 | — |
반응 단계
A mixture of phthalic anhydride (60 g.), N,N-diethyl-m-toluidine (162.8 g.), aluminum chloride (120 g.) and chlorobenzene (360 ml.) was heated (75°-95° C.) during one and one-half hours, then diluted with water (200 ml., then more). More chlorobenzene (200 ml.) was added and the chlorobenzene layer was separated and steam distilled. Addition of sodium hydroxide solution (10%) to a solution of the residue in dilute sulfuric acid (20%, 250 ml.) afforded 2-(2-methyl-4-(diethylamino)benzoyl)benzoic acid (IV: Y2 = CH3, Y'4 = (CH3CH2)2N, Z4 = Z"5 = Z"6 = Z7 = H).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04032527 |
| 출처 데이터셋 | uspto-grants-1977_06 |
| ORD ID | ord-c838bc84aeed453ca7bf0e4e8d147cdf |
| 출처 메모 | uspto-grants-1977_06 |