Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Triethylamine → Benzyl 4-((tert-butoxycarbonyl)amino)piperidine-1-carboxylate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Triethylamine | HCID 8471 | — |
| 반응물 | Benzyl chloroformate | HCID 10387 | — |
| 반응물 | 4-(N-Boc-amino)piperidine | HCID 723833 | — |
| 생성물 | Benzyl 4-((tert-butoxycarbonyl)amino)piperidine-1-carboxylate | HCID 21981786 | 81.1% |
반응 단계
The same operation as in Example (227a) was performed using 4-[(tert-butoxycarbonyl)amino]piperidine (2.00 g, 9.99 mmol), benzyl chloroformate (2.14 mL, 15.0 mmol) and triethylamine (3.48 mL, 25.0 mmol), to obtain 2.71 g of the title compound as a white solid (81%).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08536197B2 |
| 출처 데이터셋 | uspto-grants-2013_09 |
| ORD ID | ord-62ef6d9df10048689be273132c9cefaf |
| 출처 메모 | uspto-grants-2013_09 |