Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
1,3-Dithiolane → Diethylether ethylacetate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 1,3-Dithiolane | HCID 20970 | — |
| 반응물 | N-(3-Aminopropyl)morpholine | HCID 61055 | — |
| 반응물 | Ph2CHCO-Leu-Phe-COOEt | HCID 131719396 | — |
| 생성물 | Diethylether ethylacetate | HCID 21584169 | 20% |
반응 단계
This compound was synthesized from 1,3-dithiolane derivative of Ph2CHCO-Leu-Phe-COOEt and N-aminopropylmorpholine, and purified by column chromatography using AcOEt followed by crystallization from AcOEt/ether (20% yield). Yellow solid, single spot on TLC, Rf =0.45 (AcOET/CH3OH 9:1), mp 158°-160° C. 1H NMR (CDCl3) ok, MS (FAB) m/e=627 (M+1). Anal: calcd. for C37H46N4O5, 626; C, 70.90; H, 7.40; N, 8.94. Found, C, 70.05; H, 7.43; N, 8.68.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05514694 |
| 출처 데이터셋 | uspto-grants-1996_05 |
| ORD ID | ord-a0c4a16670544afa9b01d20d786d28fa |
| 출처 메모 | uspto-grants-1996_05 |