Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Acetyl chloride → N-heptylacetamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Acetyl chloride | HCID 6367 | — |
| 반응물 | 1-Heptanamine | HCID 8127 | — |
| 반응물 | Triethylamine | HCID 8471 | — |
| 용매 | Dichloromethane | HCID 6344 | — |
| 생성물 | N-heptylacetamide | HCID 347488 | — |
반응 단계
To a solution of 5.0 gms of 1-aminoheptane in 150 ml of CH2Cl2, is added 10.9 ml of Et3N followed by 2.79 ml of acetyl chloride. The reaction mixture is stirred at room temperature for 18 hours and then concentrated under vacuum. The residue obtained is partitioned between ethyl acetate and an aqueous 2N HCl solution; and after separating, the organic layer is washed with aqueous saturated NaHCO3, then brine, and dried over Na2SO4. After filtration and concentration, N-heptylacetamide is obtained as a clear liquid.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05516767 |
| 출처 데이터셋 | uspto-grants-1996_05 |
| ORD ID | ord-809b151bcabc4d149aa7636a5c1e1031 |
| 출처 메모 | uspto-grants-1996_05 |