Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Stannous Chloride → 4-Aminothiophene-2-carboxylic acid
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Stannous Chloride | HCID 24479 | — |
| 반응물 | 4-Nitrothiophene-2-carboxylic acid | HCID 268680 | — |
| 용매 | Hydrochloric Acid | HCID 313 | — |
| 생성물 | 4-Aminothiophene-2-carboxylic acid | HCID 6456065 | 72.3% |
반응 단계
4-Nitro-2-thiophenecarboxylic acid (1 g, 5.7 mmol) was added with stirring to a solution of SnCl2. 2H2O (3.25 g, 14.4 mmol) in concentrated HCl (10 ml). The mixture was stirred for 6 hours at ambient temperature and purified by subjecting to chromatography on HP20SS resin, using water as eluant, to give the title compound (0.59 g, 71%).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05519015 |
| 출처 데이터셋 | uspto-grants-1996_05 |
| ORD ID | ord-98016bcfbf334080811ded153d6acb72 |
| 출처 메모 | uspto-grants-1996_05 |