Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Water → 5-Methoxy-2-nitrobenzaldehyde
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Water | HCID 962 | — |
| 반응물 | Methyl iodide | HCID 6328 | — |
| 반응물 | Potassium Carbonate | HCID 11430 | — |
| 반응물 | 5-Hydroxy-2-nitrobenzaldehyde | HCID 39211 | — |
| 용매 | Dimethylformamide | HCID 6228 | — |
| 생성물 | 5-Methoxy-2-nitrobenzaldehyde | HCID 230371 | — |
반응 단계
Methyl iodide (23.34 g, 0.165 mol) and potassium carbonate (22.73 g, 0.165 mol) are added to a solution of 5-hydroxy-2-nitrobenzaldehyde (25 g, 0.149 mol) in N,N-dimethylformamide. The reaction mixture is stirred at room temperature for 18 hours and poured into water. The resultant aqueous mixture is extracted with ethyl acetate. The organic extracts are combined, washed with brine, dried over anhydrous sodium sulfate and concentrated in vacuo to give the title product as a brown solid, mp 89°-90° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05519133 |
| 출처 데이터셋 | uspto-grants-1996_05 |
| ORD ID | ord-224ad460d3ae43619f358d38970013a6 |
| 출처 메모 | uspto-grants-1996_05 |