Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
ethyl N-carbonylcarbamate → ethyl N-diethoxyphosphorylcarbonylcarbamate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | ethyl N-carbonylcarbamate | HCID 300166 | — |
| 반응물 | Diethylphosphite | HCID 3780918 | — |
| 촉매 | Triethylamine | HCID 8471 | — |
| 용매 | Dichloromethane | HCID 6344 | — |
| 생성물 | ethyl N-diethoxyphosphorylcarbonylcarbamate | HCID 21415674 | — |
반응 단계
To a solution of 11.0 parts of diethylphosphite in 175 parts of methylene chloride and 4 drops of triethyl amine was added 10.0 parts of ethoxycarbonyl isocyanate. The solution was refluxed for 3 hours. Removing the solvent under reduced pressure left 18.5 parts of colorless oil which partially crystallized. The crystals were washed with cyclohexane to give 7.3 parts of ethyl N-(diethylphosphonocarbonyl)carbamate, m.p. 57°-64°, The proton nmr spectrum was consistent with this structure. (δNH = 10.0 ppm)
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04043794 |
| 출처 데이터셋 | uspto-grants-1977_08 |
| ORD ID | ord-56762ca4829e47c7a9e1d4357a3606d8 |
| 출처 메모 | uspto-grants-1977_08 |