참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Thionyl Chloride | HCID 24386 | — |
| 반응물 | [1-(triphenylmethyl)-1H-imidazol-4-yl]methanol | HCID 382182 | — |
| 용매 | Chloroform | HCID 6212 | — |
| 생성물 | 4-(Chloromethyl)-1-trityl-1H-imidazole | HCID 2763176 | — |
반응 단계
The product from Step B is dissolved in chloroform and cooled to 0° C. under nitrogen. Thionyl chloride (molar equivalent) is added slowly via syringe. The reaction is stirred for 30 min, and extracted with sodium bicarbonate solution. The organic phase is dried over magnesium sulfate, filtered and concentrated to provide the title compound.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US05891889 |
|---|
| 출처 데이터셋 | uspto-grants-1999_04 |
|---|
| ORD ID | ord-20695b29fecf4994adf4ae877b640bc6 |
|---|
| 출처 메모 | uspto-grants-1999_04 |
|---|
