Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Hydrocodone → Oxycodone
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Hydrocodone | HCID 5284569 | — |
| 반응물 | Hydromorphone | HCID 5284570 | — |
| 반응물 | Morphine | HCID 5288826 | — |
| 생성물 | Oxycodone | HCID 5284603 | — |
반응 단계
To a 150 mL beaker was charged 10.0 g oxycodone hydrochloride and 100 mL water. Concentrated ammonium hydroxide (2.6 grams) was then added to bring the pH to approximately 9. The product was collected by vacuum filtration, washed with cold water and dried for about 5 hours under vacuum to provide 8.3 g (93% yield) of a white solid consistent in structure with oxycodone free base. This procedure was used to prepare hydrocodone, hydromorphone and morphine free base as needed.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08476291B1 |
| 출처 데이터셋 | uspto-grants-2013_07 |
| ORD ID | ord-8f3e3ff1c440472ba752da96d96b5d33 |
| 출처 메모 | uspto-grants-2013_07 |