Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Sodium Cyanate → 1-cyclohexylmethyl-4-(4-isopropyl-phenyl)-6,7-dimethoxy-1H-quinazolin-2-one
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Sodium Cyanate | HCID 517096 | — |
| 반응물 | (2-Amino-4,5-dimethoxy-phenyl)-(4-isopropyl-phenyl)-methanone | HCID 59259172 | — |
| 용매 | Acetic Acid | HCID 176 | — |
| 생성물 | 1-cyclohexylmethyl-4-(4-isopropyl-phenyl)-6,7-dimethoxy-1H-quinazolin-2-one | HCID 10159139 | — |
반응 단계
To a solution of 50 mg (0.126 mmol) (2-amino-4,5-dimethoxy-phenyl)-(4-isopropyl-phenyl)-methanone in 1 ml acetic acid are added 8 mg (0.126 mmol) sodium cyanate. After stirring for 24 h at rt the solvent is evaporated and the residue is extracted with dichloromethane/0.1 M NaOH. Recrystallisation from ether/hexanes yields the title compound.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08476286B2 |
| 출처 데이터셋 | uspto-grants-2013_07 |
| ORD ID | ord-29066ebe71f347c19c134ecf0c9aa638 |
| 출처 메모 | uspto-grants-2013_07 |