Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Dextroamphetamine → (S)-N-(4-iodobenzylidene)-1-phenylpropan-2-amine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Dextroamphetamine | HCID 5826 | — |
| 반응물 | Sulfuric acid magnesium salt (1:1) | HCID 24083 | — |
| 반응물 | 4-Iodobenzaldehyde | HCID 96657 | — |
| 용매 | Benzene | HCID 241 | — |
| 생성물 | (S)-N-(4-iodobenzylidene)-1-phenylpropan-2-amine | HCID 59536338 | — |
반응 단계
To a solution of (S)-1-phenylpropan-2-amine (0.500 g, 3698 μmol) in benzene (5 mL) was added 4-iodobenzaldehyde (858 mg, 3698 μmol) and MgSO4 (1.000 g, 8308 μmol) and the suspension stirred at RT 4 h. The suspension was filtered and the solid washed with benzene (2×2 mL). The combined filtrates were concentrated to give (S)—N-(4-iodobenzylidene)-1-phenylpropan-2-amine as a yellow oil which was used without purification in the next step.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08476297B2 |
| 출처 데이터셋 | uspto-grants-2013_07 |
| ORD ID | ord-7a8b283067424cb0a14f1367a09d912a |
| 출처 메모 | uspto-grants-2013_07 |