Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
2,6-Lutidine → 2,6-Dimethylpyridine N-oxide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 2,6-Lutidine | HCID 7937 | — |
| 반응물 | m-Chloroperbenzoic acid | HCID 70297 | — |
| 용매 | Chloroform | HCID 6212 | — |
| 생성물 | 2,6-Dimethylpyridine N-oxide | HCID 14083 | 88.4% |
반응 단계
To a 0° C. solution of 2,6-dimethylpyridine (1.0 g, 0.009 mol) in CHCl3 (25 mL) was added mCPBA (3.17 g, 0.01 mol). The reaction mixture was then stirred for 12 h at RT, quenched with a saturated Na2CO3 solution. The organic layer was separated, dried over Na2SO4 and concentrated in vacuo to afford 2,6-dimethylpyridine 1-oxide (980 mg, 85%) as a solid.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08481534B2 |
| 출처 데이터셋 | uspto-grants-2013_07 |
| ORD ID | ord-5694c3e4dc404594a53163c478a732f0 |
| 출처 메모 | uspto-grants-2013_07 |