Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Ethanol → ethyl (2R)-5-oxopyrrolidine-2-carboxylate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Ethanol | HCID 702 | — |
| 반응물 | D-Pyroglutamic acid | HCID 439685 | — |
| 용매 | Sulfuric Acid | HCID 1118 | — |
| 생성물 | ethyl (2R)-5-oxopyrrolidine-2-carboxylate | HCID 643508 | — |
반응 단계
To a solution of D-pyroglutamic acid (compound I-A, 20.4 g, 0.16 mol) in 100 mL of EtOH, 1.2 mL of conc. sulfuric acid was added. The mixture was heated under reflux overnight. Solvent was removed under reduced pressure to give (R)-ethyl 5-oxopyrrolidine-2-carboxylate (compound II-AA).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08541418B2 |
| 출처 데이터셋 | uspto-grants-2013_09 |
| ORD ID | ord-a7bce6362165468fa455f7ec24641f1b |
| 출처 메모 | uspto-grants-2013_09 |