Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
4-(1H-Imidazol-2-yl)-pyridine → (R)-8-cyclopropyl-7-ethyl-5-methyl-2-(2-(pyridin-4-yl)-1H-imidazol-1-yl)-7,8-dihydropteridin-6(5H)-one
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 4-(1H-Imidazol-2-yl)-pyridine | HCID 316817 | — |
| 반응물 | (R)-2-chloro-8-cyclopropyl-7-ethyl-5-methyl-7,8-dihydropteridin-6(5H)-one | HCID 58405375 | — |
| 생성물 | (R)-8-cyclopropyl-7-ethyl-5-methyl-2-(2-(pyridin-4-yl)-1H-imidazol-1-yl)-7,8-dihydropteridin-6(5H)-one | HCID 58405779 | — |
반응 단계
The title compound was prepared similarly to the methods described in Example 77, with Intermediate O instead of Intermediate C and with 4-(1H-imidazol-2-yl)pyridine instead of 2-phenyl-1H-imidazole. LCMS: 376.1 m/z (M+H)+; ret. Time: 3.90 min (Analytical Method C).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08541418B2 |
| 출처 데이터셋 | uspto-grants-2013_09 |
| ORD ID | ord-138f1e0e2443425985b5fa47c1c6cf2c |
| 출처 메모 | uspto-grants-2013_09 |