Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
5-Aminobenzimidazole → HCID 51030962, 화합물
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 5-Aminobenzimidazole | HCID 13623 | — |
| 반응물 | 1,1'-Carbonyldiimidazole | HCID 68263 | — |
| 반응물 | Trimethylsilyl cyanide | HCID 82115 | — |
| 반응물 | 4-(2-Morpholinoethoxy)benzaldehyde | HCID 3719902 | — |
| 생성물 | HCID 51030962 | HCID 51030962 | — |
반응 단계
The compound was synthesized as ditrifluoroacetate salt starting from 5-aminobenzimidazole (0.585 g, 4.4 mmol), 4-(2-morpholinoethoxy)benzaldehyde (0.941 g, 4 mmol), TMSCN (0.5 mL, 4 mmol), PdC (10%, 0.02 g), TEA (1.34 mL, 9.6 mmol), di-(imidazol-1-yl)methanone (0.582 g, 3.6 mmol) as described in method 2. The product was purified by means of preparative HPLC.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08486940B2 |
| 출처 데이터셋 | uspto-grants-2013_07 |
| ORD ID | ord-a09b34d2006140fb960c4f057a2d045f |
| 출처 메모 | uspto-grants-2013_07 |