Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
3-(3-Trifluoromethylphenyl)propanoic acid → 1-[4-(methylthio)phenyl]-6-[5-[2-[3-(trifluoromethyl)phenyl]ethyl]-1,3,4-oxadiazol-2-yl]-1H-benzimidazole
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 3-(3-Trifluoromethylphenyl)propanoic acid | HCID 2777683 | — |
| 반응물 | 1-[4-(methylthio)phenyl]-1H-benzimidazole-6-carbohydrazide | HCID 44482294 | — |
| 생성물 | 1-[4-(methylthio)phenyl]-6-[5-[2-[3-(trifluoromethyl)phenyl]ethyl]-1,3,4-oxadiazol-2-yl]-1H-benzimidazole | HCID 68664679 | 70% |
반응 단계
In the same manner as in Example 14 and using 1-[4-(methylthio)phenyl]-1H-benzimidazole-6-carbohydrazide instead of 1H-benzotriazole-5-carbohydrazide and using 3-[3-(trifluoromethyl)phenyl]propionic acid instead of 3-(3-cyanophenyl)propionic acid, the title compound (yield 70%) was obtained as colorless crystals.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08492378B2 |
| 출처 데이터셋 | uspto-grants-2013_07 |
| ORD ID | ord-33a5ec177f5546f19bbb908dec4a6f00 |
| 출처 메모 | uspto-grants-2013_07 |