Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
N-(2-Chloroethyl)dibenzylamine → 3-(2-Dibenzylaminoethoxy)salicylic acid methyl ester
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | N-(2-Chloroethyl)dibenzylamine | HCID 5820 | — |
| 반응물 | Potassium Carbonate | HCID 11430 | — |
| 반응물 | Methyl 2,3-Dihydroxybenzoate | HCID 75484 | — |
| 용매 | Acetonitrile | HCID 6342 | — |
| 생성물 | 3-(2-Dibenzylaminoethoxy)salicylic acid methyl ester | HCID 53929446 | — |
반응 단계
2,3-dihydroxybenzoic acid methyl ester is reacted in the presence of potassium carbonate in acetonitrile with 1.1 equivalents of 1-dibenzylamino-2-chloroethane for 18 hours at 82°. The crude 3-(2-dibenzylaminoethoxy)salicyclic acid methyl ester obtained after working up is put to further use without further purification.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04727067 |
| 출처 데이터셋 | uspto-grants-1988_02 |
| ORD ID | ord-bdd53f2aa794405982b767a086f662bc |
| 출처 메모 | uspto-grants-1988_02 |