Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
2-Amino-4,6-difluoropyrimidine → 4,6-difluoro-N-((2-(4-fluorophenyl)-6-methylimidazo[1,2-a]pyridin-3-yl)methyl)pyrimidin-2-amine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 2-Amino-4,6-difluoropyrimidine | HCID 1201480 | — |
| 반응물 | 3-(Chloromethyl)-2-(4-fluorophenyl)-6-methylimidazo[1,2-a]pyridine hydrochloride | HCID 67028789 | — |
| 생성물 | 4,6-difluoro-N-((2-(4-fluorophenyl)-6-methylimidazo[1,2-a]pyridin-3-yl)methyl)pyrimidin-2-amine | HCID 67028731 | 39% |
반응 단계
The title compound was prepared according to Method A and the experimentals described for compound 139 from 3-(chloromethyl)-2-(4-fluorophenyl)-6-methylimidazo[1,2-a]pyridine hydrochloride and 4,6-difluoropyrimidin-2-amine. (0.23 g, 39% yield), M/e+ 370.1 for C19H14F3N5 (M+H)+.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08497278B2 |
| 출처 데이터셋 | uspto-grants-2013_07 |
| ORD ID | ord-981d85149e954738bab827775927c37d |
| 출처 메모 | uspto-grants-2013_07 |