Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Donepezil Oxalate → Donepezil
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Donepezil Oxalate | HCID 11397232 | — |
| 용매 | Water | HCID 962 | — |
| 생성물 | Donepezil | HCID 3152 | — |
반응 단계
Donepezil oxalate is dissolved in water and basified. Donepezil base thus obtained, is extracted in a suitable solvent and acidified with aqueous hydrochloric acid. The solvent is evaporated and aqueous acidic solution of Donepezil hydrochloride is lyophilized to obtain Donepezil hydrochloride amorphous form.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07186842B2 |
| 출처 데이터셋 | uspto-grants-2007_03 |
| ORD ID | ord-89100b8d2c32439cb682a641e143944c |
| 출처 메모 | uspto-grants-2007_03 |