Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
2,5-dibromo-N'-[4-(octyloxy)benzoyl]benzohydrazide → 2-(2,5-Dibromophenyl)-5-[4-(octyloxy)phenyl]-1,3,4-oxadiazole
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 2,5-dibromo-N'-[4-(octyloxy)benzoyl]benzohydrazide | HCID 21982102 | — |
| 용매 | Phosphorus oxychloride | HCID 24813 | — |
| 생성물 | 2-(2,5-Dibromophenyl)-5-[4-(octyloxy)phenyl]-1,3,4-oxadiazole | HCID 21982073 | 89% |
반응 단계
A mixture of 2,5-dibromo-N′-[4-(octyloxy)benzoyl]benzohydrazide (39.1 g, 0.0743 mol) and phosphorus oxychloride (203 mL) was refluxed for 8 hrs. Unreacted phosphorus oxychloride was distilled off and the residue poured onto crushed ice. The precipitated solid was collected by filtration and re-crystallized from EtOH/water to give 33.6 g (89% yield) 2-(2,5-dibromophenyl)-5-[4-(octyloxy)phenyl]1,3,4-oxadiazole.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07192657B2 |
| 출처 데이터셋 | uspto-grants-2007_03 |
| ORD ID | ord-155e2d177b64459fbe2de377a1f1cb55 |
| 출처 메모 | uspto-grants-2007_03 |