Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
p-Xylyl bromide → HCID 178436363, 화합물
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | p-Xylyl bromide | HCID 7721 | — |
| 반응물 | Potassium Carbonate | HCID 11430 | — |
| 반응물 | N-(4-Ethylbenzyl)-1H-benzo[d]imidazol-5-amine | HCID 67443948 | — |
| 생성물 | HCID 178436363 | HCID 178436363 | — |
반응 단계
The compound was synthesized starting from N-(4-ethylbenzyl)benzimidazol-5-amine (251 mg; 1 mmol; 1 eq.), 4-methylbenzylbromide (204 mg; 1.1 mmol; 1.1 eq.) and K2CO3 (152 mg; 1.1 mmol; 1.1 eq.) according to method 6; Yield: 0.131 g (36.9%); MS m/z: 356.5 [M+H]+; 1H-NMR (500 MHz, DMSO d6): δ 1.14 (t, 3H, 3J=7.6 Hz); 2.25 (s, 3H); 2.55 (q, 2H, 3J=7.6 Hz); 4.60 (s, 4H); 6.68 (br s, 1H); 6.72 (dd, 1H, 4J=1.8 Hz, 3J=8.9 Hz); 7.09-7.19 (m, 8H); 7.32 (d, 1H, 3J=8.9 Hz); 7.89 (s, 1H); 11.88 (br s, 1H); HPLC (METHOD [A]): rt 18.62 min (100%)
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08541596B2 |
| 출처 데이터셋 | uspto-grants-2013_09 |
| ORD ID | ord-83534f1344dd4b949d27294816ba1012 |
| 출처 메모 | uspto-grants-2013_09 |