참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Cyclohexyl methyl ketone | HCID 13207 | — |
| 반응물 | tert-Butoxy bis(dimethylamino)methane | HCID 79885 | — |
| 생성물 | 1-Cyclohexyl-3-dimethylamino-propenone | HCID 11095241 | 93% |
반응 단계
A mixture of 3.0 g (23.8 mmol) of cyclohexyl methyl ketone and 4.56 g (26.2 mmol) of t-butoxybis(dimethylamino)methane (Bredereck's reagent) was stirred at 60° C. overnight. The reaction mixture was then concentrated to give 4.0 g (93% yield) of 1-cyclohexyl-3-dimethylamino-propenone as an orange oil as indicated by 1H NMR. This product was used in the next reaction without any further purification.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US07196111B2 |
|---|
| 출처 데이터셋 | uspto-grants-2007_03 |
|---|
| ORD ID | ord-cbb6055354164bfe8509e4c4b6195761 |
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| 출처 메모 | uspto-grants-2007_03 |
|---|
