Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
4-(6-Methoxy-2-naphthalenyl)-3-buten-2-one → Nabumetone
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 4-(6-Methoxy-2-naphthalenyl)-3-buten-2-one | HCID 53409926 | — |
| 반응물 | HCID 178418361 | HCID 178418361 | — |
| 촉매 | Palladium | HCID 23938 | — |
| 용매 | Ethyl Acetate | HCID 8857 | — |
| 생성물 | Nabumetone | HCID 4409 | 69.7% |
반응 단계
4-(6-Methoxy-2-naphthyl)-3-butene-2-one (32 g) in ethyl acetate (500 ml) was shaken at room temperature over 10% Pd/C (3 g) under atmospheric pressure hydrogen until no further uptake of hydrogen occurred to yield 4-(6-methoxy-2-naphthyl)butan-2-one (22.5 g), mp. 78.5° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04061779 |
| 출처 데이터셋 | uspto-grants-1977_12 |
| ORD ID | ord-87349bb778f24e4ea4971911c536f41d |
| 출처 메모 | uspto-grants-1977_12 |