Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
p-Acetoxybenzoyl chloride → 4-Acetoxy-2'-[2-(1-methyl-2-piperidyl)ethyl]benzanilide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | p-Acetoxybenzoyl chloride | HCID 2756254 | — |
| 반응물 | 2-(2-Aminophenethyl)-1-methylpiperidine | HCID 11085282 | — |
| 용매 | Pyridine | HCID 1049 | — |
| 생성물 | 4-Acetoxy-2'-[2-(1-methyl-2-piperidyl)ethyl]benzanilide | HCID 20560030 | — |
반응 단계
Reaction of 2-(o-aminophenethyl)-1-methylpiperidine with p-acetoxybenzoyl chloride in pyridine according to Example 1 provides 4-acetoxy-2'-[2-(1-methyl-2-piperidyl)-ethyl]benzanilide. Analytically pure product is obtained by crystallization from isopropyl ether, m.p. 88°-108° C. (corr.). The broad melting point of the analytically pure material is due to polymorphism.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04064254 |
| 출처 데이터셋 | uspto-grants-1977_12 |
| ORD ID | ord-71b55c2e83f747ee9807e6e6ee065a50 |
| 출처 메모 | uspto-grants-1977_12 |