Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Acetic Anhydride → Nitric Acid
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Acetic Anhydride | HCID 7918 | — |
| 반응물 | Isosorbide | HCID 12597 | — |
| 반응물 | Isosorbide 2-mononitrate | HCID 62989 | — |
| 생성물 | Nitric Acid | HCID 944 | — |
| 생성물 | Acetic Anhydride | HCID 7918 | — |
반응 단계
The following process for preparing 1,4:3,6-dianhydro-D-glucitol 2-nitrate is described: acylating 1,4:3,6-dianhydro-D-glucitol with 0.5 to 1.5 molar equivalents of acetic anhydride in the presence of an acid catalyst, nitrating the product so obtained with a mixture of nitric acid and acetic anhydride, hydrolyzing the product so obtained in the presence of an inorganic base and isolating 1,4:3,6-dianhydro-D-glucitol 2-nitrate. The 1,4:3,6-dianhydro-D-glucitol 2-nitrate is useful as a coronary vasodilator.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04065488 |
| 출처 데이터셋 | uspto-grants-1977_12 |
| ORD ID | ord-7f6d1bd3a7d64f5cabbc56f6cd46a244 |
| 출처 메모 | uspto-grants-1977_12 |