Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
2-(Methylamino)ethanol → 2-{2-[N-(2-Hydroxyethyl)methylamino]-5-thiadiazolyl}-1-methyl-5-nitroimidazole
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 2-(Methylamino)ethanol | HCID 8016 | — |
| 반응물 | Piperidine | HCID 8082 | — |
| 반응물 | 2-(2-Piperidino-5-thiadiazolyl)-1-methyl-5-nitroimidazole | HCID 21390837 | — |
| 생성물 | 2-{2-[N-(2-Hydroxyethyl)methylamino]-5-thiadiazolyl}-1-methyl-5-nitroimidazole | HCID 68118756 | — |
반응 단계
The preparation of the above compound is carried out essentially as described for the 2-piperidino derivative (Example 28), an equivalent of N-methylethanolamine replacing the piperidine. The pure compound melts at 158°-160° C. after recrystallization from methanol.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04065567 |
| 출처 데이터셋 | uspto-grants-1977_12 |
| ORD ID | ord-da559262e11a4cd4991ae08c78971761 |
| 출처 메모 | uspto-grants-1977_12 |