Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Piperazine → 2-[2-(1-Piperazinyl)-5-thiadiazolyl]-1-methyl-5-nitroimidazole
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Piperazine | HCID 4837 | — |
| 반응물 | Piperidine | HCID 8082 | — |
| 반응물 | 2-(2-Piperidino-5-thiadiazolyl)-1-methyl-5-nitroimidazole | HCID 21390837 | — |
| 생성물 | 2-[2-(1-Piperazinyl)-5-thiadiazolyl]-1-methyl-5-nitroimidazole | HCID 21390830 | — |
반응 단계
The preparation of the subject compound is carried out essentially as described for the 2-piperidino derivative (Example 28), two equivalents of piperazine replacing the piperidine. The crude project is recrystallized from 2-methoxyethanol to yield the pure compound melting at 240°-241° C. ;cl EXAMPLE 24
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04065567 |
| 출처 데이터셋 | uspto-grants-1977_12 |
| ORD ID | ord-12914646f91d4db4b530caf5515c91e9 |
| 출처 메모 | uspto-grants-1977_12 |