Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Sodium Azide → 5-(2-Chloro-4-trifluoromethylphenoxy)-2-nitrophenyl azide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Sodium Azide | HCID 33557 | — |
| 반응물 | Benzene, 2-chloro-1-(3,4-dinitrophenoxy)-4-(trifluoromethyl)- | HCID 156238 | — |
| 용매 | Acetone | HCID 180 | — |
| 생성물 | 5-(2-Chloro-4-trifluoromethylphenoxy)-2-nitrophenyl azide | HCID 13505357 | — |
반응 단계
A mixture of 4-(2-chloro-4-trifluoromethylphenoxy)-1,2-dinitrobenzene (2.0 g, 5.5 mmol) and sodium azide (1.1 g, 16.6 mmol) in acetone (25 ml) is heated under reflux for 3.5 hours. The reaction is then cooled and filtered, and the filtrate is stripped. The residue is taken up in chloroform, washed with water (2X) and with brine, dried, stripped and purified by preparative thin layer chromatography (prep. TLC) (silica gel, eluting with 15% ethyl acetate/hexane) to give 5-(2-chloro-4-trifluoromethylphenoxy)-2-nitrophenyl azide.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04544400 |
| 출처 데이터셋 | uspto-grants-1985_10 |
| ORD ID | ord-6be467e2eaa24931ab7484da4a7a0218 |
| 출처 메모 | uspto-grants-1985_10 |