Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Ethanol → 3-(2,6-Dimethylphenylamino)-2-butanone
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Ethanol | HCID 702 | — |
| 반응물 | N,N-Dimethylaniline | HCID 949 | — |
| 반응물 | 2-Butanone, 3-bromo- | HCID 13142 | — |
| 반응물 | Sodium Bicarbonate | HCID 516892 | — |
| 용매 | Dichloromethane | HCID 6344 | — |
| 생성물 | 3-(2,6-Dimethylphenylamino)-2-butanone | HCID 12491475 | — |
반응 단계
A mixture of 121 g (1 mol) dimethylaniline, 149 g (1 mol) 3-bromo-2-butanone and 126 g (1.5 mol) sodium bicarbonate in 500 ml ethanol was stirred at 60°-70° C. for about 18 hours. The reaction mixture was filtered and the filtrate evaporated under reduced pressure to give an oil. The oil was taken up in dichloromethane, dried over magnesium sulfate, treated with silica, filtered and evaporated under reduced pressure to give 174.8 g of 3-(2,6-dimethylphenylamino)-2-butanone as a light amber oil. The infrared spectrum of the product showed strong carbonyl absorption at 5.8 microns.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04174210 |
| 출처 데이터셋 | uspto-grants-1979_11 |
| ORD ID | ord-55fe877fc0b649889e8d08545b4a3111 |
| 출처 메모 | uspto-grants-1979_11 |