참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Ammonium Hydroxide | HCID 14923 | — |
| 반응물 | Phosphorus oxychloride | HCID 24813 | — |
| 반응물 | HCID 178437532 | HCID 178437532 | — |
| 용매 | Chloroform | HCID 6212 | — |
| 생성물 | 5-chloro-2-ethyl-7-methyl-3H-Imidazo[4,5-b]pyridine | HCID 19385734 | — |
반응 단계
A mixture of the N-oxide (29.75 g, 0.168 mol), CHCl3 (25 mL) and POCl3 (160 mL) was heated to 80° C. for 1 hours. After pouring over ice, the mixture was neutralized by careful addition of NH4OH and extracted with EtOAc. Concentration gave 23.8 g of 5-chloro-2-ethyl-7-methylimidazo[4,5-b]pyridine as a solid.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US05157026 |
|---|
| 출처 데이터셋 | uspto-grants-1992_10 |
|---|
| ORD ID | ord-8064d2a62fa4477887173a559f968371 |
|---|
| 출처 메모 | uspto-grants-1992_10 |
|---|
