참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Nitric Acid | HCID 944 | — |
| 반응물 | Urea | HCID 1176 | — |
| 반응물 | Benzophenone | HCID 3102 | — |
| 반응물 | Acetic Anhydride | HCID 7918 | — |
| 반응물 | N-(4-benzoylphenyl)acetamide | HCID 228532 | — |
| 용매 | Acetic Acid | HCID 176 | — |
| 생성물 | 4-Acetamido-3-nitrobenzophenone | HCID 596969 | 62.5% |
반응 단계
Twenty-three grams (0.1 mole) of 4-acetamidobenzophenone, 50 ml. of acetic anhydride and 20 ml. of acetic acid were stirred together. A solution of 90 percent nitric acid (15 ml.), 10 ml. of acetic acid and 0.2 g. of urea was added dropwise to the benzophenone mixture. The reaction mixture was maintained at a temperature of about 50° C. during the nitration. The mixture was stirred at ambient temperature whereupon the mixture became very thick. The thick slurry was poured over ice and the insoluble product was filtered to yield 17.7 g. (62.5 percent yield) of 4-acetamido-3-nitrobenzophenone.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US04174454 |
|---|
| 출처 데이터셋 | uspto-grants-1979_11 |
|---|
| ORD ID | ord-a5455505a191425295375af1cb977a14 |
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| 출처 메모 | uspto-grants-1979_11 |
|---|
