Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
1-Bromonaphthalene → 1,1'-Binaphthyl
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 1-Bromonaphthalene | HCID 7001 | — |
| 반응물 | Calciumoxide | HCID 6850728 | — |
| 반응물 | Sodium naphthalene-1-sulfinate | HCID 23681220 | — |
| 촉매 | 1,2-Bis(diphenylphosphino)ethane | HCID 74267 | — |
| 촉매 | palladium(II) acetate | HCID 167845 | — |
| 용매 | N-methyl-2-pyrrolidone | HCID 13387 | — |
| 생성물 | 1,1'-Binaphthyl | HCID 11789 | 64% |
반응 단계
4.28 g (20 mmol) of sodium 1-naphthalenesulfinate, 4.14 g (20 mmol) of 1-bromonaphthalene, 0.0225 g (0.1 mmol) of palladium acetate, 0.0478 g (0.12 mmol) of 1,2-bis(diphenylphosphino)ethane, 6.73 g (120 mmol) of calcium oxide and 60 ml of N-methyl-2-pyrrolidone were placed in a 100 ml round bottom flask and reacted at 150° C. in a nitrogen gas stream for 8 hours. After the completion of the reaction, the reaction mixture was analyzed by means of high performance liquid chromatography. The analysis showed that 12.8 mmol (yield 64%) of 1,1'-binaphthyl was formed in the reaction mixture solution.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05159082 |
| 출처 데이터셋 | uspto-grants-1992_10 |
| ORD ID | ord-af30cc3459374cf5900863cea6334567 |
| 출처 메모 | uspto-grants-1992_10 |