Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Cycloheptene → 2-[(1-Cyclohepten-3-yl)thio]acetaldehyde
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Cycloheptene | HCID 12363 | — |
| 반응물 | p-Toluenesulfonic acid monohydrate | HCID 521998 | — |
| 용매 | Propan-2-one--water (1/1) | HCID 18366337 | — |
| 생성물 | 2-[(1-Cyclohepten-3-yl)thio]acetaldehyde | HCID 12620961 | 100% |
반응 단계
A solution of 108.13 g (0.443 mole) of 3-[2,2-diethoxyethyl)thio]-1-cycloheptene in 1000 ml of acetone/water, 9:1 was treated with 1.1 g of p-toluenesulfonic acid hydrate and heated under reflux for 1.0 hour, cooled, and concentrated. The residue was partitioned between ether/10% sodium bicarbonate. The aqueous phase was further extracted with ether. The organic extracts were pooled, dried over magnesium sulfate, and evaporated to afford 75.30 g (0.443 mole, 100%) of 2-[(1-cyclohepten-3-yl)thio]acetaldehyde as a colorless oil.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04175086 |
| 출처 데이터셋 | uspto-grants-1979_11 |
| ORD ID | ord-d2e4355203d449d08f1cb4c0210246dc |
| 출처 메모 | uspto-grants-1979_11 |