Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Triethylamine → Ethyl N-(4-methyl-2-oxazolyl)carbamate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Triethylamine | HCID 8471 | — |
| 반응물 | Ethyl chloroformate | HCID 10928 | — |
| 반응물 | 4-Methyloxazol-2-amine | HCID 535824 | — |
| 용매 | Diethyl Ether | HCID 3283 | — |
| 생성물 | Ethyl N-(4-methyl-2-oxazolyl)carbamate | HCID 23468960 | — |
반응 단계
Ethyl chloroformate (1.05 ml, 0.011 mol) was added dropwise to a stirred solution of 2-amino-4-methyloxazole (1.0 g, 0.010 mol) and triethylamine (1.5 ml, 0.011 mol) in dry ether (50 ml) at 5°-10° C. The mixture was stirred for 2 hours at 0°-5° C. then the white solid was filtered off and washed well with water to remove triethylamine hydrochloride. Residue (0.5 g) was recrystallised from chloroform-petroleum spirit, m.p. 126° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04175131 |
| 출처 데이터셋 | uspto-grants-1979_11 |
| ORD ID | ord-293f27be2e06490ea50a569219038416 |
| 출처 메모 | uspto-grants-1979_11 |