참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Acetone | HCID 180 | — |
| 반응물 | Methanol | HCID 887 | — |
| 반응물 | 1,4-Butane sultone | HCID 15411 | — |
| 반응물 | N-(3-(Dimethylamino)propyl)methacrylamide | HCID 78882 | — |
| 용매 | Acetonitrile | HCID 6342 | — |
| 생성물 | 4-((3-Methacrylamidopropyl)dimethylammonio)butane-1-sulfonate | HCID 86662543 | 85.5% |
반응 단계
In 380 ml of acetonitrile were dissolved 130 g (0.764 mol) of N-[3-(dimethylamino)propyl]methacrylamide, 104 g of butanesultone and 234 mg of 4-hydroxy-2,2,6,6-tetramethylpiperidinoxy and the solution was heated at 70° C. for 6 hours. After allowing to cooling, to the reaction mixture were added 1,350 ml of acetone and 150 ml of methanol and the mixture was stirred at room temperature for one hour. The crystals deposited were collected by filtration and thoroughly washed with acetone to obtain 200.0 g (yield: 85%) of 4-sulfonatobutyl[3-(methacryloylamino)propyl]dimethylammonium.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US08637221B2 |
|---|
| 출처 데이터셋 | uspto-grants-2014_01 |
|---|
| ORD ID | ord-d96a2ec609454e248a967f7ae9380428 |
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| 출처 메모 | uspto-grants-2014_01 |
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