Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Phenylacetonitrile → Ethyl 2-dimethylamino-5-cyano-5-phenyl-2,4-pentadienoate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Phenylacetonitrile | HCID 8794 | — |
| 반응물 | N-(dimethylamino-3-ethoxycarbonylpropenylidene)-N-methylmethanaminium tetrafluoroborate | HCID 86743575 | — |
| 반응물 | Diethyl 2-dimethylamino-5-phenylthio-2,4-hexadienedioate | HCID 86743580 | — |
| 용매 | Sodium ethoxide | HCID 2723922 | — |
| 생성물 | Ethyl 2-dimethylamino-5-cyano-5-phenyl-2,4-pentadienoate | HCID 54027283 | 66.9% |
반응 단계
The procedure is as in Example 2 for the preparation of diethyl 2-dimethylamino-5-phenylthio-2,4-hexadienedioate, starting with N-(3-dimethylamino-3-ethoxycarbonylpropenylidene)-N-methylmethanaminium tetrafluoroborate (57.2 g), a 2M ethanolic solution of sodium ethylate (105 cc) and benzyl cyanide (23.4 g). Ethyl 2-dimethylamino-5-cyano-5-phenyl-2,4-pentadienoate (36.1 g), m.p. 67° C., is obtained.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04886835 |
| 출처 데이터셋 | uspto-grants-1989_12 |
| ORD ID | ord-01806bcea28f4f9cb4632d80fa6ae209 |
| 출처 메모 | uspto-grants-1989_12 |