참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | tert-Butyl isothiocyanate | HCID 11544 | — |
| 반응물 | (R)-2-Aminohexan-1-ol | HCID 6994402 | — |
| 용매 | Ethanol | HCID 702 | — |
| 생성물 | N-(tert-butyl)-N'-[(1R)-1-butyl-2-hydroxyethyl]thiourea | HCID 86584433 | — |
반응 단계
The process is performed as in Example 2, starting with 1.14 g of (2R)-2-amino-2-butyl-1-ethanol and 1.36 cm3 of tert-butyl isothiocyanate in 15 cm3 of ethanol, with stirring for 18 hours at a temperature in the region of 20° C. and then for 3 hours in the region of 60° C. After concentration of the reaction medium under reduced pressure (5 kPa) at a temperature in the region of 40° C. 2.38 g of N-(tert-butyl)-N′-[(1R)-1-butyl-2-hydroxyethyl]thiourea are obtained in the form of a yellow oil. Infrared spectrum (CH2Cl2):3620; 4430; 4410; 2960; 1560; 1500; 1395; 1375 and 1205 cm−1.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US06699895B2 |
|---|
| 출처 데이터셋 | uspto-grants-2004_03 |
|---|
| ORD ID | ord-de21f8aef6d745878a87ecda1bb5be3a |
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| 출처 메모 | uspto-grants-2004_03 |
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