Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Potassium Hydroxide → 6-Benzyloxy-1,2,3,4-tetrahydro-naphthalene-2-carboxylic Acid
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Potassium Hydroxide | HCID 14797 | — |
| 반응물 | 6-Benzyloxy-1,2,3,4-tetrahydro-naphthalene-2-carboxylic Acid Benzyl Ester | HCID 18960134 | — |
| 용매 | Water ethanol | HCID 19096565 | — |
| 생성물 | 6-Benzyloxy-1,2,3,4-tetrahydro-naphthalene-2-carboxylic Acid | HCID 19069973 | 95% |
반응 단계
A solution of 6-benzyloxy-1,2,3,4-tetrahydro-naphthalene-2-carboxylic acid benzyl ester (30) (1 equi.) and potassium hydroxide (3.5 equi.) in water-ethanol (1:1) (25 mL/mmole) was stirred at 80 C temperature for 2 h, cooled to room temperature, and quenched with hydrochloric acid (5%), the resulting white solid was filtered, washed with water, and dried under vacuum to give 6-benzyloxy-1,2,3,4-tetrahydro-naphthalene-2-carboxylic acid (31) as a white solid (95%).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06703082B1 |
| 출처 데이터셋 | uspto-grants-2004_03 |
| ORD ID | ord-37916f1e508f4919b9f142becd1a9cca |
| 출처 메모 | uspto-grants-2004_03 |