Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
4-Fluorophenylboronic acid → Emd-50929
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 4-Fluorophenylboronic acid | HCID 285645 | — |
| 반응물 | Methyl 5-bromopyridine-3-carboxylate | HCID 699336 | — |
| 반응물 | Methyl 5-(4-fluorophenyl)nicotinate | HCID 22743456 | — |
| 생성물 | Emd-50929 | HCID 11378949 | — |
반응 단계
15.3 g of methyl 5-(4-fluorophenyl)nicotinate (obtainable by Suzuki coupling of methyl 5-bromopyridine-3-carboxylate with 4-fluorobenzeneboronic acid analogously to Example 1 or 2) are saponified by conventional methods to give 5-(4-fluorophenyl)nicotinic acid.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06703509B2 |
| 출처 데이터셋 | uspto-grants-2004_03 |
| ORD ID | ord-cd26b86a68d2414683332086861e6679 |
| 출처 메모 | uspto-grants-2004_03 |