Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
3-Hydroxypropionic acid → beta-Carboxyethyl 10,11-Dihydro-11-oxodibenzo[b,f]thiepin-3-carboxylate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 3-Hydroxypropionic acid | HCID 68152 | — |
| 반응물 | Sodium | HCID 5360545 | — |
| 반응물 | 3-Chlorocarbonyl-10,11-dihydro-11-oxodibenzo[b,f]thiepin | HCID 20270211 | — |
| 용매 | Tetrahydrofuran | HCID 8028 | — |
| 생성물 | beta-Carboxyethyl 10,11-Dihydro-11-oxodibenzo[b,f]thiepin-3-carboxylate | HCID 20270225 | — |
반응 단계
Dissolve 1.0 gm. of 3-chlorocarbonyl-10,11-dihydro-11-oxodibenzo[b,f]thiepin in 20 cc. of tetrahydrofuran and add 1.0 gm. of the sodium salt of β-hydroxypropionic acid. Stir the mixture at room temperature for 18 hours. Filter and evaporate the filtrate to dryness. Recrystallize the solid residue from ethanol to obtain the title product.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04536507 |
| 출처 데이터셋 | uspto-grants-1985_08 |
| ORD ID | ord-8905073b85194a5088311a6580caff38 |
| 출처 메모 | uspto-grants-1985_08 |