Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Thionyl Chloride → 1-benzyl-2-(chloromethyl)-1H-imidazole hydrochloride
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Thionyl Chloride | HCID 24386 | — |
| 반응물 | (1-benzyl-1H-imidazol-2-yl)methanol | HCID 311778 | — |
| 용매 | Dichloromethane | HCID 6344 | — |
| 생성물 | 1-benzyl-2-(chloromethyl)-1H-imidazole hydrochloride | HCID 2779243 | — |
반응 단계
A solution of 1-benzyl-2-hydroxymethyl-imidazole (6 g, 32 mmol) in methylenechloride is slowly added thionylchloride (3.5 ml, 48 mmol) and after stirring at ambient temperature for 4 hours the reaction mixture is concentrated in vacuo yielding 1-benzyl-2-chloromethyl-imidazole, hydrochloride.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05296493 |
| 출처 데이터셋 | uspto-grants-1994_03 |
| ORD ID | ord-bcd326844a504e529e1c11e39bf5243e |
| 출처 메모 | uspto-grants-1994_03 |