Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
4-Hydroxybenzaldehyde → (-)-N-(p-hydroxybenzylidene)-1-(p-bromophenyl)ethylamine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 4-Hydroxybenzaldehyde | HCID 126 | — |
| 반응물 | (R)-4-bromo-alpha-methylbenzylamine | HCID 853000 | — |
| 용매 | Ethanol | HCID 702 | — |
| 생성물 | (-)-N-(p-hydroxybenzylidene)-1-(p-bromophenyl)ethylamine | HCID 135802981 | 100% |
반응 단계
4.44 g (0.0222 mole) of (R)-(+)-1-(p-bromophenyl)ethylamine and 2.85 g (0.0233 mole) of p-hydroxybenzaldehyde were dissolved in 30 ml of ethyl alcohol, and the solution thus formed was stirred under reflux for 3 hours. After the completion of the reaction, the reaction mixture was concentrated under reduced pressure, and refined by a column chromatography using 30 g of silica gel to give 6.75 g of (-)-N-(p-hydroxybenzylidene)-1-(p-bromophenyl)ethylamine.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05298660 |
| 출처 데이터셋 | uspto-grants-1994_03 |
| ORD ID | ord-c85c00e039224d0fbdfb183b9c19d456 |
| 출처 메모 | uspto-grants-1994_03 |