Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Methyl morpholine oxide → 4-Phenyl-3-furaldehyde
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Methyl morpholine oxide | HCID 82029 | — |
| 반응물 | (4-Phenylfuran-3-yl)methanol | HCID 15037154 | — |
| 촉매 | HCID 178419074 | HCID 178419074 | — |
| 용매 | Dichloromethane | HCID 6344 | — |
| 생성물 | 4-Phenyl-3-furaldehyde | HCID 15037148 | — |
반응 단계
A mixture of 3-phenyl-4-furylmethanol (Compound 19, 458 mg, 2.63 mmol), powdered 4A molecular sieves (500 mg), 4-methyl-morpholine-N-oxide (462 mg, 3.95 mmol) and tetrapropylammonium perruthenate (46 mg, 0.13 mmol) in anhydrous dichloromethane (40 ml) were stirred at room temperature for 3 hours. Residue was filtered through silica and concentrated to a brown oil which was purified by flash chromatography on silica using 10% ethyl ether/hexanes to give the titled aldehyde.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05298633 |
| 출처 데이터셋 | uspto-grants-1994_03 |
| ORD ID | ord-f25d39c3e0214fe99b24cd420b86fba7 |
| 출처 메모 | uspto-grants-1994_03 |