Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Myristyl bromide → 3,4-Bis(tetradecyloxy)benzoic acid methyl ester
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Myristyl bromide | HCID 8208 | — |
| 반응물 | Potassium Carbonate | HCID 11430 | — |
| 반응물 | Methyl 3,4-Dihydroxybenzoate | HCID 287064 | — |
| 용매 | Dimethylformamide | HCID 6228 | — |
| 생성물 | 3,4-Bis(tetradecyloxy)benzoic acid methyl ester | HCID 12048557 | 30% |
반응 단계
A mixture of 1.0 g (6.6 mmol) of 3,4-dihydroxybenzoic acid methyl ester, 4.1 ml (14 mmol) of 1-bromotetradecane and 2.5 g (17.9 mmol) of potassium carbonate in 50 ml of DMF was stirred and heated at 100° for 65 hours. The solvent was removed using high vacuum, water was added to the residue and the product was extracted with ethyl acetate. The dried extract was concentrated to a solid which was recrystallized from methanol-water to give 1.1 g (30% yield, mp 49°-50°) of 3,4-bis(tetradecyloxy)benzoic acid methyl ester.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05298652 |
| 출처 데이터셋 | uspto-grants-1994_03 |
| ORD ID | ord-983be0e066a3453ebfe4c6f6734ffa9f |
| 출처 메모 | uspto-grants-1994_03 |