Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
3-Methyl-5-nitroisoquinoline → 3-Methylisoquinolin-5-amine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 3-Methyl-5-nitroisoquinoline | HCID 274973 | — |
| 촉매 | Palladium | HCID 23938 | — |
| 용매 | Methanol | HCID 887 | — |
| 생성물 | 3-Methylisoquinolin-5-amine | HCID 12212055 | 76.1% |
반응 단계
A solution of (D1) (1 g, 5.3 mM) and 10% palladium on charcoal (0.15 g) in methanol (40 ml) was hydrogenated at atmospheric pressure for 1 h. The catalyst was filtered off and the filtrate concentrated under reduced pressure to afford the product as a grey solid (0.64 g).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07528150B2 |
| 출처 데이터셋 | uspto-grants-2009_05 |
| ORD ID | ord-75455a89fbf143aba118e50ac228915c |
| 출처 메모 | uspto-grants-2009_05 |