Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
4-tert-Butylphenylboronic acid → 1,4-Bis[5-(4-t-butylphenyl)-2-pyridyl]hexahydro-1,4-diazepine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 4-tert-Butylphenylboronic acid | HCID 2734320 | — |
| 반응물 | 1,4-Bis(5-bromo-2-pyridyl)hexahydro-1,4-diazepine | HCID 12991593 | — |
| 생성물 | 1,4-Bis[5-(4-t-butylphenyl)-2-pyridyl]hexahydro-1,4-diazepine | HCID 12991599 | 45.1% |
반응 단계
Following the procedure of Example 1, crude crystals were obtained from the 1,4-bis(5-bromo-2-pyridyl)hexahydro-1,4-diazepine (206.0 mg, 0.500 mmol) synthesized in Reference Example 1 and 4-t-butylphenylboronic acid (226.0 mg, 1.20 mmol). The crude crystals were recrystallized from chloroform-hexane to yield the title compound as colorless needles (melting point: 268.0-270.0° C.) (117.0 mg, yield: 42%).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06706703B2 |
| 출처 데이터셋 | uspto-grants-2004_03 |
| ORD ID | ord-96b60b7afc914f32b96110c2fcb78aa9 |
| 출처 메모 | uspto-grants-2004_03 |